Materials for Drug & Gene Delivery

Symposium Chair
Steven Zullo Program Director, Division of Discovery Science and Technology NIBIB/NIH
Confirmed Invited Speakers
Development of a Stable Micelle for Drug Delivery in Oncology Kevin Sill Chief Science Officer, Intezyne	TiO2-DNA Nanocomposites for Imaging and Therapeutic Applications Gayle E. Woloschak Robert E. Lurie Comprehensive Cancer Center Feinberg School of Medicine, Northwestern University
Novel Zwitterionic Liposome Approaches to Lipid Based Nucleic Acid Delivery Juliane Nguyen Ph.D., Deutsche Forschungsgemeinschaft Fellow, Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California, San Francisco	The Art of Falling Apart: Exploiting Nanomaterial Disassembly for Medicine and Pharmacy Adah Almutairi Professor, Laboratory for Bioresponsive Materials, University of California, San Diego
Development of peptide-based polymers for gene transfer to the CNS Suzie Hwang Pun Associate Professor of Bioengineering, University of Washington	Microfluidic technology enables scalable manufacture of limit-size lipid nanoparticles (lsLNP): size matters for the next generation of therapeutic drug delivery systems James Taylor CEO and Co-Founder, Precision NanoSystems
Targeting Laser Treatment to Inaccessible Tumors Using Nanoparticle Drug Delivery Vehicles Ann-Marie Broome Associate Professor, Medical University of South Carolina	New Liposomes for Cancer and Chronic Disease Treatment Mark Hayes Co-Founder & Senior Scientist, ZoneOne Pharma Inc
Thresholdless Nanoscale Lasesrs Mercedeh Khajavikhan Staff Researcher, UCSD

Symposium Sessions
	Tuesday June 19
10:30	Materials for Drug & Gene Delivery Keynotes I
12:30	Networking Lunch - Expo
1:30	TechConnect IP Partnering: Biotech & Biosciences
1:30	Materials for Drug & Gene Delivery Keynotes II
2:45	TechConnect IP Partnering: Medical, Pharma, Personal Care
4:00	Financing Emerging Technology Commercialization
4:30	Expo Reception and Poster Session I (4:30 - 6:30)
	Materials for Drug & Gene Delivery
	Wednesday June 20
11:00	Materials for Drug & Gene Delivery III
12:30	Networking Lunch - Expo
1:00	NNI - Director’s Networking Session, National Nanotechnology Coordination Office
1:30	Exhibit and Poster Session II
	Materials for Drug & Gene Delivery
3:30	Materials for Drug & Gene Delivery IV
5:30	TechConnect Innovation Showcase Reception
6:00	CTSI Utility Technology Challenge Awards and Reception
	Thursday June 21
10:00	National Nanotechnology Initiative Triennial Review
12:30	National Innovation Showcase - Networking Lunch (available for purchase)
2:30	TechConnect Start-Up Partnering: Medical, Pharma, Personal Care
4:00	TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences
4:00	TechConnect National Innovation Showcase, Reception & Poster Session III
Symposium Program
	Tuesday June 19
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10:30	Materials for Drug & Gene Delivery Keynotes I	Grand Ballroom D
	Session chair: Steven Zullo, NIBIB National Institutes of Health, US
10:30	Development of a Stable Micelle for Drug Delivery in Oncology K. Sill, Intezyne, US (bio)
11:00	Development of peptide-based polymers for gene transfer to the CNS S.H. Pun, University of Washington, US (bio)
11:30	The Art of Falling Apart: Exploiting Nanomaterial Disassembly for Medicine and Pharmacy A. Almutairi, University of California, San Diego, US (bio)
12:00	Novel Zwitterionic Liposome Approaches to Lipid Based Nucleic Acid Delivery J. Nguyen, C. Walsh, M. Motion, F.C. Szoka, University of California, San Francisco, US (bio)
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12:30	Networking Lunch - Expo	Expo Hall AB
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1:30	TechConnect IP Partnering: Biotech & Biosciences	Room 212
	Session chair: Lynn Foster, BPT Pharma, Reviewers: Scott Carter, Latham & Watkins, Julia Ljubimova, Cedars-Sinai Medical Center, US
1:30	New Compound Activates Broad Spectrum Lung Immunity N. Zelver, Montana State University Technology Transfer, US
1:40	Novel Agents to Enhance Tolerance to an Immunogen N. Zelver, Montana State University Technology Transfer, US
1:50	Glycine N-methyltransferase (GNMT) Animal model and use thereof Y.M. Chen, National Yang-Ming University, TW
2:00	Novel Single Dose Sterilant for Male and Female Companion and Feral Animals R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:10	A Novel Protein Folding System R. Kulkani, University of Kansas Center for Technology Commercialization, US
2:20	Non-Viral Nanoparticle-Based Delivery System M. Malhotra, McGill University, CA
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1:30	Materials for Drug & Gene Delivery Keynotes II	Grand Ballroom D
	Session chair: Steven Zullo, NIBIB National Institutes of Health, US
1:30	TiO2-DNA Nanocomposites for Imaging and Therapeutic Applications G.E. Woloschak, Northwestern University, US (bio)
2:00	Microfluidic technology enables scalable manufacture of limit-size lipid nanoparticles (lsLNP): size matters for the next generation of therapeutic drug delivery systems. J. Taylor, Precision Nanosystems, US
2:30	Targeting Laser Treatment to Inaccessible Tumors Using Nanoparticle Drug Delivery Vehicles A.-M. Broome, Case Western Reserve University, US (bio)
3:00	Thresholdless Nanoscale Lasers M. Khajavikhan, University of Minnesota, US
3:30	New Liposomes for Cancer and Chronic Disease Treatment C. Noble, ZeroOne Pharma, Inc., US
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2:45	TechConnect IP Partnering: Medical, Pharma, Personal Care	Room 207
	Session chair: Belen Martinez-Lopez, CaramelTech, MX, Reviewers: Schuyler Corry, Invtitrogen, Mark Wittman, Beyond Lucid Technologies, Cece Gassner, City of Boise, US
2:45	NCap - NanoPorous Materials for Sustained Release W. Daniell, NanoScape AG, DE
2:55	Medical Nano-magnetic Drug Guidance A. Harel, NanoMed Targeting Systems Inc., US
3:05	Universal Optofluidic Chip for Ultra-Sensitive Raman Analysis of Liquid S. Mak, University of Toronto, CA
3:15	Next generation single dose vaccine adjuvants S. Niewiesk, The Ohio State University, US
3:25	Double Clad Fiber Coupler Allowing 3D Endoscopy T. Martinuzzo, Univalor, CA
3:35	Nanogold Assays for Direct Detection of Nucleic Acids of High Burden Infections H. Azzazy, The American University in Cairo, EG
3:45	A Liquid Crystal Polymer (LCP) Membrane MEMS Sensor for Flow Rate and Flow Direction Sensing, Medical and Environmental Applications L.M. Sim, Industry Liaison Office, National University of Singapore (NUS), SG
3:55	Fluorescent and Luminescent Labels for Diagnostic Imaging and Sensitive Detection of Biopolymers S. Pillai, New Jersey Institute of Technology, US
4:05	Leukocyte coping capacity: stress-testing at your fingertips D. Sarphie, Oxford MediStress Ltd, UK
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4:00	Financing Emerging Technology Commercialization	Room 203
	Session chair: Tom Klein, Greenberg Traurig, US
-	P. Dhingra, NanoStellar, US
-	B. Segal, Lockheed Martin, US
-	B. Horangic, North Bridge, US
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4:30	Expo Reception and Poster Session I (4:30 - 6:30)	Expo Hall AB
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	Materials for Drug & Gene Delivery
-	Controlled- Release Antibiotic Nanoparticles for Cranial Transplantation and Bone Grafting A.N. Adusumilli, S. Dammalapati, P.K.-L. Fu, Governors State University, US
-	Surface Functionalized Multicomponent Envelope Type Nanosystems for Improved Gene Delivery D. Pozzi, V. Orlando, G. Augusti Tocco, S. Biagioni, F. Cardarelli, A. Bifone, G. Caraccioloa, Sapienza University of Rome, IT
-	Nanoscale iron trimesate metal organic framework as potential platform for active nucleoside analogues delivery V. Agostoni, T. Chalati, P. Horcajada, H. Willaime, P. Couvreur, R. Anand, S. Monti, C. Serre, R. Gref, UMR CNRS 8612, FR
-	Nanoparticles of iron trimesate metal organic framework (MIL100) for drugs encapsulation and delivery, comparisons between two different syntheses. H. Willaime, V. Agostoni, P. Horcajada, C. Serre, R. Gref, Université Paris-Sud, FR
-	Nanoparticle platform for therapeutic siRNA delivery to HER2 positive breast cancer W. Ngamcherdtrakul, J. Morry, T. Sangvanich, R. Lee, Z. Hu, S. Gu, J. Gray, W. Yantasee, Oregon Health and Science University, US
-	Preparation and evaluation of some carriers for the immobilization of β-Galactosidase N.Y.F. Almehbad, Faculty of Education for Female Teachers Najran, SA
-	A Novel Single Step Method of Synthesizing Large Unilamellar Liposomes for Biomedical Applications S.M. Phapal, P. Sunthar, Indian Institute of Technology Bombay, IN
-	Multidrug resistance protein P-gp interaction with nanoparticles (fullerenes and carbon nanotubes) to assess drug delivery to the CNS: a molecular docking study S. Shityakov, C. Förster, University of Würzburg, DE
-	Cell penetrating peptide mediated delivery of has-miRNA-29b to promote mesenchymal stem cell differentiation into osteogenic lineage J.S. Suh, J.Y. Lee, Y.S. Choi, C.P. Chung, Y.J. Park, Seoul National University, KR
-	Metal Oxide Nanoparticle-Induced Changes in 20S Proteasome Activity C.A. Falaschetti, T. Paunesku, S.S. Chou, M.H. Song, J-T Jang, V.P. Dravid, J. Cheon, G.E. Woloschak, Northwestern University, Feinberg School of Medicine, US
	Wednesday June 20
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11:00	Materials for Drug & Gene Delivery III	Great America 3
	Session chair: Steven Zullo, NIBIB National Institutes of Health, US
11:00	Controlling the Intracellular Distribution of Agents with Core/Shell Particles Made from Particle Blends K.K. Tran, H. Shen, University of Washinton, US
11:20	Multifunctionalized gold nanoparticles for controlled drug-release by non-linear excitation V. Voliani, F. Ricci, G. Signore, R. Nifosì, S. Luin, F. Beltram, Center for nanotechnology innovation @NST, Istituto italiano di tecnologia and Scuola normale superiore, IT
11:40	Multifunctional Gold Nanorod-Based Drug/SiRNA Nanocarriers for Targeted Neuroendocrine Cancer Therapy Y. Xiao, R. Jaskula-Sztulb, H. Chen, S. Gong, University of Wisconsin-Madison, US
12:00	Targeted Nucleoprotein Nanodevices for Diagnosis and Delivery E. Singer, K. Munson, T. Wilson, S. Smith, Beckman Research Institute of the City of Hope, US
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12:30	Networking Lunch - Expo	Exhibit Hall AB
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1:00	NNI - Director’s Networking Session, National Nanotechnology Coordination Office	Exhibit Hall A
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1:30	Exhibit and Poster Session II	Exhibit Hall AB
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	Materials for Drug & Gene Delivery
-	Understanding Adhesion of Bioactive Polymers on Hydrophobic and Hydrophilic Surfaces. V. Vyas, B.D. Huey, University of Connecticut, US
-	Supramolecular assemblies of cisplatin and polyelectrolytes: preparation, characterization and activity against cancer cells D.B. Vieira, V. Kim, D.F.S. Petri, C.F.M. Menck, A.M. Carmona-Ribeiro, Universidade de São Paulo, BR
-	Orally Delivered Polymeric nanoparticles of Lopinavir: Development and Statistical optimization, in vitro and ex vivo studies G. Joshi, K.K. Sawant, M S University of Baroda, IN
-	Nanostructured cellulose materials: adsorption of antibiotics onto cellulose fibers functionalized with glycidylmethacrylate for the manufacturing of antibacterial fabrics E. Vismara, G. Torri, A. Valerio, G. Graziani, A. Montanelli, L. Melone, Politecnico di Milano, IT
-	Properties of Hydrophobized Chitosan-Insulin Nanoparticles with different hydrophobic chain sizes. E. Robles, E. Villar, J. Juárez, P. Taboada, M.-G. Burboa, M. Alatorre, V. Mosquera, M.-A. Valdez, Universidad de Sonora, MX
-	Self Assembled Nanostructures of Triblock Co-polymer and Plasmid DNA for GeneDelivery H.K. Daima, S. Shankar, P.R. Selvakannan, S.K. Bhargava, V. Bansal, RMIT University, AU
-	In vitro anticancer activity of poly(3-hydroxybutyrate) nanoparticles loaded with antitumor drug Paclitaxel S.G. Yakovlev, A.P. Bonartsev, D.V. Bagrov, Yu.M. Efremov, A.P. Boskhomdzhiev, E.V. Filatova, P.V. Ivanov, T.K. Makhina, G.A. Bonartseva, A.N.Bach’s Institute of Biochemistry Russian Academy of Sciences, RU
-	Nanospray Dryer Employed in Nanoencapsulated Production A.M. Oliveira, N.N.P. Cerize, K.L. Guimarães, J.G.R. Poco, A.S. Tunussi, D.C.S. Patto, Institute of Technological Research – IPT, BR
-	Sequential Surface Functionalization by Polyoxometalates and Lysine Renders Non-toxic Gold Nanoparticles Strong Antibacterial Agents H.K. Daima, P.R. Selvakannan, S.K. Bhargava, V. Bansal, RMIT University, AU
-	Encapsulation and Characterization of BSA in PLA-PEG Nanoparticles as a Model for Chlamydia trachomatis rMOMP-278 Protein Nanovaccine Delivery System M. Taha, S.R. Singh, C. Moore, R. Agee, V.A. Dennis, Alabama State University, US
-	Counting and Sizing Protein Aggregates Down to 0.15 micron Using New Focused Beam Light Scattering Technology P. O’Hagan, D.F. Nicoli, K. Hasapidis, Particle Sizing Systems, US
-	Surfactant Effect on Intercellular Transport of DNA, Proteins, and Electrolytes D. Assan, X. Gao, J.C.K. Lai, S.W. Leung, Idaho State U, US
-	Drug diffusion transport models for nanoporous material A. Ziemys, M. Milosevic, M. Ferrari, M. Kojic, The Methodist Hospital Research Institute, US
-	Development of PHEMA-Chitosan nanospheres and encapsulation of RSV-F DNA vaccine E. Eroglu, A.B. Waffo, V.A. Dennis, S.R. Singh, Alabama State University, US
-	Nanoparticle Analysis with a Tunable Pore Sensor for Monitoring of Drug Delivery Systems Y. Ganor, Izon Science Ltd, US
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3:30	Materials for Drug & Gene Delivery IV	Great America 2
	Session chair: Steven Zullo, NIBIB National Institutes of Health, US
3:30	Drug Delivery with Light-Activated Gold-Coated Liposomes G.V. Orsinger, S.J. Leung, S.S. Knights, J.D. Williams, M. Romanowski, University of Arizona, US
3:50	Lyophilisomes: novel protein capsules as drug delivery system E. van Bracht, P.J. Geutjes, R.G. Wismans, E. Oosterwijk, T.H. Kuppevelt, W.F. Daamen, Radboud University Nijmegen Medical Centre, NL
4:10	Electrically-Controlled Drug Release System to Assist Wound Healing S. Zhu, J. Mbugua, M. Chase, J. Maskrod, J.H. Jung, T. Nicholson III, E. Fabrizio, R. Mercado, Crosslink, US
4:30	Designing Responsive Materials with Chemically Amplified Sensitivity to NIR light N. Fomina, C. McFearin, M. Sermsakdi, J. Morachis, A. Almutairi, University of California at San Diego, US
4:50	Dual Modal Gene Expression and Silencing Using Viral/Nonviral Chimeric Nanoparticles for Synergistic Gene Therapy S.K. Cho, T. Luu, S. Wong, Y.J. Kwon, UC Irvine, US
5:10	Triple protection delivery system for retinaldehyde: Preparation, skin penetration and controlled release at the hair follicles. P. Supmuang, S. Wanichwecharungruang, Chulalongkorn University, TH
5:30	Electrospun Nanofibrous Scaffold for Controlled Drug Delivery V. Leung, R. Hartwell, E. Faure, H. Yang, A. Ghahary, F. Ko, University of British Columbia, CA
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5:30	TechConnect Innovation Showcase Reception	Expo Hall CD
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6:00	CTSI Utility Technology Challenge Awards and Reception	Expo Theater 1
	Session chair: Patti Glaza, Arsenal Venture Partners, US
	Thursday June 21
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10:00	National Nanotechnology Initiative Triennial Review	Great America 1
	Session chair: Erik Svedberg, National Materials and Manufacturing, National Academies, US
10:00	NNI Town Hall Meeting E. Svedberg, National Nanotechnology Initiative, US
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12:30	National Innovation Showcase - Networking Lunch (available for purchase)	Expo Hall CD
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2:30	TechConnect Start-Up Partnering: Medical, Pharma, Personal Care	Expo Theater 2
	Session chair: Paul Prendergast, Merchant & Gould, US
2:30	Topical Skin Adhesive W.B. Jeon, IntuitiveMediCorp, KR
2:40	Nano-Magnetic drug targeting A. Harel, NanoMed Targeting Systems Inc., US
2:50	Leukocyte coping capacity: stress-testing at your fingertips D. Sarphie, Oxford MediStress Ltd, US
3:00	Reagent-free nanobiomimetic electrochemical sensing platform E. Chen, Advanced Biomimetic Sensors, Inc., US
3:10	Magnetic nanotechnology for targeted cancer treatment T. Mitrelias, Cavendish NanoTherapeutics, UK
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4:00	TechConnect Start-Up Partnering: Biotech, Biomaterials & Biosciences	Expo Theater 2
	Session chair: Paul Prendergast, Merchant & Gould, US
4:00	Laser Transmission Spectroscopy C. Tanner, LightSprite, LLC, US
4:10	Novel Shape Memory foam devices for neurovascular and other vascular applications S. Biswas, Shape Memory Therapeutics, US
4:20	Low-power, high brightness, high-resolution LED Light S. Kang, Lux World Co., Ltd., KR
4:30	Disruptive wireless silicon platform for disposable wireless healthcare sensors S. Magar, HMicro, Inc., US
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4:00	TechConnect National Innovation Showcase, Reception & Poster Session III	Expo Hall CD

Special Symposium

Biocompatible materials with nano-scale structure hold great promise as controlled release reservoirs for delivery of both small-molecule drugs and various classes of biomacromolecules, such as peptides, proteins, plasmid DNA and synthetic oligodeoxynucleotides. Promising delivery systems include microcapsules, liposomes, macromolecular conjugates, nanoparticles, dendrimers, and biological nanostuctures such benign viruses and bacteriophages. This symposium will focus on success stories and reports of exciting new nanostructured materials and approaches for drug and gene delivery.

Topics & Application Areas

• Targeting at Molecular, Cellular & Higher Levels
• Novel Delivery Systems
• Modes of Entry
• Controlled Release Systems
• Microcapsules
• Liposomes
• Polymer-based delivery systems
• Antibody Targeting
• Protein/Peptide Delivery
• Pharmacodynamics
• Nanomedicine clinical trials: challenges & results
• Other

 

Sponsor & Exhibitor Opportunities

	Exhibit and Showcase
	Become a Sponsor

Please contact: Denise Lee

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Program Tracks

Fabrication & Characterization
Advanced Materials
Electronics & Microsystems
Medical & Biotech
Energy & Environment
Business & Partnering

 

2012 TechConnect Corporate Acceleration Partners:

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Sponsorship Opportunities: Contact Denise Lee

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