Materials for Drug & Gene Delivery

Symposium Co-Chairs

Steven Zullo
Program Officer
NIBIB/NIH

Thomas Anchordoquy
Professor, Skaggs School of Pharmacy and Pharmaceutical Sciences
University of Colorado School of Pharmacy

Key Speakers

Paving a Path for the Clinic – Preclinical Characterization of Nanomedicine
Maggie Scully
Scientist I, Nanotechnology Characterization Laboratory, Frederick National Laboratory for Cancer Research

MRI-Guided Focused Ultrasound: A Transformative, State-of-the-Art Technology for 21st Century Medicine
Victor Frenkel
Associate Professor, Dept. of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine

Zwitterlation - A Promising Strategy beyond PEGylation
Shaoyi Jiang
Boeing-Roundhill Professor of Chemical Engineering, University of Washington

Nanomedicine: From High Tech to Global Health
Robert K. Prud'homme
Professor and Director Program in Engr. Biology, Princeton University

Symposium Sessions
	Monday May 14
1:30	Cancer Therapy & Diagnostics Delivery
	Tuesday May 15
10:30	Encapsulation, Targeting, and Delivery
1:30	The Future of Drug & Gene Delivery: Panel Discussion
	Wednesday May 16
8:30	Novel Drug Delivery Systems
3:30	Drug & Gene Delivery: Posters

Symposium Program
	Monday May 14

1:30	Cancer Therapy & Diagnostics Delivery	252 A
	Session chair: Anil Patri, U.S. Food and Drug Administration, US; Steve Zullo, NIBIB/NIH, US
1:30	Innovation that Enables the Encapsulation of Sparingly Soluble Drugs for Delivery in Liposomes (invited presentation) F.C. Szoka, C.O. Noble, M.E. Hayes, University of California, San Francisco, US
1:55	MRI-Guided Focused Ultrasound: A Transformative, State-of-the-Art Technology for 21st Century Medicine (invited presentation) P. Anastasiadis, University of Maryland School of Medicine, US
2:20	Evaluation of Pyrrolobenzodiazepine loaded Nanoparticles : A potential targeted drug delivery approach (invited presentation) P. Tyagi, MedImmune, US
2:45	Silver nanoparticles for use in precision medicine-based cancer therapies J. Swanner, C.D. Fahrenholtz, P.-A. Vidi, K.L. Cook, M. McMahon, I. Tenvooren, B.W. Bernish, J.J. Sears, G.L. Donati, R.N. Singh, Wake Forest School of Medicine, US
3:05	Functional Polylactide-based Systems for Delivery of Cancer Therapeutics C. Cheng, H. Sun, Y. Yu, C-K Chen, J. Zou, University at Buffalo, the State University of New York, US
3:25	In vitro and In vivo evaluation of 2-amino-7(8)-fluorophenazine N5,N10-dioxide within polymeric micelles as theranostic agents N. Lecot, Centro de Investigaciones Nucleares. Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay., UY
3:45	Paving a Path for the Clinic – Preclinical Characterization of Nanomedicine (invited presentation) M. Scully, Frederick National Laboratory for Cancer Research, US
	Tuesday May 15

10:30	Encapsulation, Targeting, and Delivery	253 A
	Session chair: Thomas Anchordoquy, University of Colorado, US: Steven Zullo, NIBIB/NIH, US
10:30	Nanomedicine: From High Tech to Global Health (invited presentation) R. Prud'homme, Princeton University, US
10:55	Precise Phage-navigating Metastatic Breast Cancer-targeted Paclitaxel-Micell Nanomedicines V.A. Petrenko, V.P. Torchilin, Auburn University, US
11:15	Bedaquiline loaded lipid nanoparticles: a promising candidate for TB treatment D. Jary, A. Hibbitts, T. Lozano-Fernandez, D. Pérez, A. Lucia, J.A. Ainsa, D. Codony, C. Freire, N. Redinger, U. Schaible, J.M. Coya Raboso, L. Tailleux, F. Navarro, CEA LETI, FR
11:35	Zwitterionic Polymer Surfactants for Drug Delivery Z. Cao, Wayne State University, US
11:55	Three-Dimensional Microfabrication of Biodegradable Polymers for Controlled Drug Delivery T.D. Nguyen, University of Connecticut, US

1:30	The Future of Drug & Gene Delivery: Panel Discussion	253 A
	Session chair: Thomas Anchordoquy, University of Colorado, US: Steven Zullo, NIBIB/NIH, US
	F.C. Szoka, ZoneOne Pharma, US
	M. Scully, National Cancer Institute, US
	P. Anastasiadis, University of Maryland School of Medicine, US
	S. Jiang, University of Washington, US
	R.K. Prud'homme, Princeton University, US
	A. Patri, U.S. Food and Drug Administration, US
	T. Anchordoquy, University of Colorado School of Pharmacy, US
	Wednesday May 16

8:30	Novel Drug Delivery Systems	262 C
	Session chair: Steven Zullo, NIBIB/NIH, US; Thomas Anchordoquy, University of Colorado, US
8:30	Zwitterlation - A Promising Strategy beyond PEGylation (invited presentation) S. Jiang, University of Washington, US
8:55	The Role of Immune Cells and Immunogenicity in Gene Delivery (invited presentation) T. Anchordoquy, University of Colorado, School of Pharmacy, US
9:20	In vivo Delivery of Nucleic Acids to Multiple Lung Cell Types Using Optimized Poly(β-amino ester) Nanoparticles J.C. Kaczmarek, K.J. Kauffman, A.K. Patel, M.W. Heartlein, F. DeRosa, D.G. Anderson, MIT, US
9:40	Hybrid Programmable Peptide Crosslinkers as Enzyme-Regulated Drug Delivery Vehicles J.L. Rouge, University of Connecticut, US
10:00	Nanostructured Lipid Carriers to Deliver HIV p24 Antigen and CpG Immunostimulant in Mice and Non-Human Primates Immunogenicity Studies E. Bayon, J. Morlieras, L. Gosse, A. Gonon, N. Bosquet, R. Le Grand, P.N. Marche, F.P. Navarro, CEA LETI, FR

3:30	Drug & Gene Delivery: Posters	2nd Floor
	Modeling of polypeptide- and polymer-conjugated nanoparticles for drug delivery application H.K. Lee, Dankook University, KR
	Improved anti-tumor activity of a novel APE/Ref-1 inhibitor using a cyclic peptide as nano drug delivery system for melanoma therapy R. Alhazmi, S. Darwish, S. Fong, K. Parang, S. Yang, Chapman University School of Pharmacy, US
	Exacerbation of amyloid beta peptide and Tau protein in the cerebrospinal fluid following Traumatic Brain Injury at Hot Environment. Neuroproetction by TiO2 nanowired delivery of cerebrolysin with tau antibodies H.S. Sharma, J.V. Lafuente, D.F. Muresanua, R.J. Castellani, M.A. Smith, A. Nozari, R. Patnaik, Z.R. Tian, A. Ozkizilcik, H. Mössler, A. Sharma, Uppsala University, Uppsala, SE
	Co-administration of TiO2 nanowired cerebrolysin and alpha melanocyte stimulating hormone has superior neuroprotective effects on brain pathology following concussive head injury after sleep deprivation A. Sharma, J.V. Lafuente, D.F. Muresanua, A. Nozari, R. Patnaik, Z.R. Tian, A. Ozkizilcik, H. Mössler, H.S. Sharma, Uppsala University, Uppsala, SE
	Intraspinal administration of TiO2 nanowired cerebrolysin with mesenchymal stem cells has superior neuroprotective effects on cord pathology and functional outcome following a focal spinal cord trauma L. Feng, A. Sharma, F. Niu, H. Huang, J.V. Lafuenta, D.F. Muresanu, A. Ozkizilcik, Z.R. Tian, H.S. Sharma, Bethune International Peace Hospital, CN
	TiO2 nanowired delivery of cerebrolysin induces superior neuroprotection following exacerbation of blast brain injury pathophysiology in diabetes D.F. Muresanu, A. Sharma, J.V. Lafuente, A. Nozari, R. Patnaik, A. Nozari, A. Ozkizilcik, Z.R. Tian, H. Mössler, H.S. Sharma, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania, RO
	Nanodelivery of Chinese traditional medicine extract of Gingko Biloba (EGb-761) induces superior neuroprotection following traumatic brain injury in heat stroke A. Sharma, D.F. Muresanu, J.V. Lafuente, Z-Q Zhang, C. Li, R. Patnaik, Z.R. Tian, A. Ozikzilcik, H.S. Sharma, Uppsala University, Uppsala, SE
	Impact of Docetaxel conjugated Nanodiamonds on Gene expression of Prostate Cancer (PC3) Cells J.D. Cedeño Ortiz, S. Joshi, S.R. Singh, K. Vig, Alabama State University, US
	CD44-Targeted Peptide-Colchicine Conjugates for Acute Gout Attacks K.A. Zoghebi, K.A. Elsaid, K. Parang, Chapman University, US
	Targeted Drug Delivery with Ultrasound: A Step Toward the Magic Bullet for Inaccessible Cancers M. Marquez, L. Frolova, M. Tartis, New Mexico Institute of Mining and Technology, US
	Biologics Delivery by inverse Flash NanoPrecipitation: Scalable Routes to Highly Loaded Particles C. Markwalter, R. Pagels, R. Prud'homme, Princeton University, US
	Nanoparticle Formulations For Enhanced Bioavailability and Stability Y. Zhang, K. Ristroph, J. Feng, S. McManus, R.K. Prud'homme, Princeton University, US

The 13th Annual Materials for Drug and Gene Delivery symposium will continue our focus on promising new materials and approaches for encapsulation, targeting & delivery for therapeutic and diagnostic applications in a range of disease areas. Submit your abstract and plan to participate in this dynamic event.