Artificial metalloenzyme catalysts through directed evolution
University of Chicago, IL, United States
University of Chicago professor Jared Lewis uses â€œdirected evolutionâ€ to develop new classes of â€œgreenâ€ catalysts and general methods for catalyst engineering. Time-consuming, expensive conventional reaction steps may be replaced with a single efficient reaction step performed at moderate temperatures in aqueous buffers using engineered catalysts with good selectivity.
Primary Application Area: Materials & Chemical
Technology Development Status: Prototype
Technology Readiness Level: TRL 4
FIGURES OF MERIT
Value Proposition: Dr. Lewis’ catalysts reduce synthetic costs and accelerate diversified library construction by replacing circuitous synthetic sequences, protection and deprotection steps, and intermediate isolation and purification steps with a single reaction step.
Organization Type: Academic/Gov Lab
Showcase Booth #: 637
GOVT/EXTERNAL FUNDING SOURCES
Government Funding/Support to Date:
Primary Sources of Funding: Federal Grant
Looking for: Both Funding and Development Partners