Pusan National University,
Keywords: engineered bacteriophage, RGD, nanofiber, vascular niche, anti-oxidant
Summary:Instructive biomaterials provide a vascular niche and protect oxidative stress in injured tissue. Herein, we demonstrated that Arg-Gly-Asp (RGD)-engineered bacteriophage nanofibers provide a vascular and anti-oxidant niche, thereby having cytoprotective functions against cellular oxidative stress. These bioinspired RGD-engineered bacteriophage nanofibers can serve as a novel therapeutic platform for ischemic diseases.