Kilogram scale production of active and stable membrane proteins in vesicles

TECHNOLOGY SUMMARY

The core capabilities of Aquaporin A/S are 1) Fermentation and purification of membrane proteins at kilogram scale 2) Design of polymersomes leading to highly stable and active membrane protein formulation 3) Development and production of water filtration membranes based on this biomimetic technique Traditionally, membrane proteins are produced in research labs or assayed directly in living cells. Aquaporin's production process constitutes the largest scale membrane proteins have ever been produced at. Further, we have proven capabilities to formulate active and stable membrane proteins in large scale and at a cost orders of magnitude lower than conventional methods. This allows a new paradigme in applications of membrane proteins, simply due to availability and cost.

AREA/MATURITY/AWARDS

Primary Application Area: Biotech, Pharma

Technology Development Status: Proven Manufacturability

Technology Readiness Level: TRL 6

Vetted Programs/Awards: Awarded with Inventor of the Year 2014 by the European Patent Office


SHOWCASE SUMMARY

Organization Type: Commercial Startup (C+)

Global Innovation Awardee

Showcase Booth #: 13M

Website: HTTP://www.aquaporin.com


GOVT/EXTERNAL FUNDING SOURCES

External Funding to Date: Aquaporin has raised capital in several rounds since its founding in 2005.