Our group specializes on the development and use of gold nanoparticles for biomedical and bioanalytical applications. We invented a nanoparticle-enabled dynamic light scattering assay (NanoDLSay) for chemical and biological detection and analysis. This technique detects the target analytes by monitoring gold nanoparticle size change upon specific binding with the target molecules and species using dynamic light scattering. This technique has so far been successfully applied for a wide range of analytes, including proteins, DNAs, viruses, toxic metal ions, and small chemicals with high to ultra-high sensitivity and excellent reproducibility. We are currently applying this technique for early cancer detection and research. We collaborate with researchers from UCF College of Medicine, MD Anderson Cancer Center Orlando, Florida Hospital Cancer Institute on various projects related to prostate cancer, breast cancer, lung cancer and pancreatic cancer detection and diagnosis.