J. Boone and A.J. Gesquiere
University of Central Florida,
Summary:Iron nanoparticles can be used for cancer treatment by ferroptosis. Ferroptosis is where iron induces the production of reactive oxygen species (ROS) that lead to the death of the cancer cell. These polymer-based nanoparticles have iron embedded in the polymer during their synthesis and are unable to be completely purified out. The purpose of these nanoparticles is to kill pancreatic cancer cells as it is one of the leading causes of cancer related death in the United States and remains there due to the lack of early diagnosis as well as rapid metastasis of the cancer. This presentation will discuss the current progress that has been made in the development of these nanoparticles for fighting pancreatic cancer.