R.A. Stillwell, T. O'Sullivan
NearWave,
United States
Keywords: optical spectroscopy, diagnostics
Summary:
Frequency domain diffuse optical spectroscopy (fd-DOS) uses modulated laser light to noninvasively image quantitative chromophore distribution and concentrations of living tissues including hemoglobin, deoxyhemoglobin, lipids and water. We present the latest progress in a new variant of the NearWave Scanner, a handheld, battery powered, all-digital hardware approach that includes both data collection and real-time display of quantitative tissue optical properties. The system is capable of displaying real-time 2D images with sample rates up to 10kHz, and 1D long-duration (1hr+) measurements with a modified front end design. Optical scattering and absorption measurements are found to be within 10% agreement as compared to a reference system. We conclude with data from a lactation study being done with a partner institution, as well as real-time imaging demonstrations of human tissue and tissue mimicking phantoms.