A. Sadik, N. Ahamad
Shahjalal University of Science and Technology, Sylhet,
Bangladesh
Keywords: rice straw, nanocellulose, scaffold, bone regeneration, tissue engineering
Summary:
Bone tissue engineering (BTE) demands biocompatible and biodegradable scaffolds that mimic the natural extracellular matrix. Cellulose, a renewable and abundant natural polymer, exhibits promising properties for bone regeneration. This study focuses on synthesizing and characterizing cellulose phosphate hydrogel, a chemically modified cellulose derivative, as a potential scaffold material for BTE. In this project, cellulose was extracted from rice straws by pretreatment with alkali and acid solutions successively, which was characterized by Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR), and UV-visible spectroscopies. Cellulose phosphate was synthesized using a facile and efficient method, using dibasic ammonium phosphate ((NH4)2HPO4) and urea (NH2-CO-NH2) solution. Its functional group was investigated by using FTIR and the structural and physicochemical properties will be further investigated by using various techniques including X-ray Diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS), and Thermogravimetric Analysis (TGA). As synthesized cellulose phosphate derivative is considered as a potential biomaterial for BTE.