* denotes 2023 Innovation Award Winner
sam
sam is a smartphone app that provides customized meal plans for people with chronic conditions such as diabetes, hypertension, high cholesterol, obesity, celiac disease and more. In addition, users have access to on-demand nutrition education and culinary medicine recipes to empower them to manage their chronic condition nutritionally.Autopilot Single-Jet 3D Electrospinning platform for Engineering Clinically Relevant 3D Topographic Fibrous Scaffolds for Biomedical Applications
Electric field-driven polymer jet self-directs its writing of fiber deposition toward a 3D collector in a silkworm-like fashion that self-constructs 3D-topographic fibrous scaffolds with high porosity, mechanical robustness, and shape memory beneficial for biomedical applications.Carbon Monoxide Prodrug and Related Delivery Systems for Therapeutics
This technology is a class of small molecule prodrugs that release carbon monoxide (CO) under specific physiological conditions with dose control and without specialized settings or external stimuli. It could be used for a wide range of medical applications such as anti-inflammation, cancer treatment, pain management, and acute kidney injury.A dissolving, sharps-free microneedle intradermal injection platform for site specific nonopioid pain relief
A single use, self-administered, dissolving microneedle array for site specific pain relief without the need of a healthcare professional. The sharps-free microneedle array provides rapid intradermal delivery without pain, bleeding, or bruising. A modified version is currently used by CDC, NIH, and UNICEF for vaccines in developing countries.Development of the Gold Nanocontructs for Infection Remediation (AuNIR)
Our technology is known as AuNIR (Gold Nanoconstructs for Infection Remediation). It is an innovative nanotechnological approach that employs an antibody-conjugated, antibiotic-loaded, gold nanocage (AuNC) solution to target MDR pathogens. This multimodal therapeutic intervention takes advantage of the synergistic effects of photodynamic therapy(PDT), photothermal therapy(PTT), and pharmacological intervention.Linear Displacement Adhesion Assay (LiDiAA)
Linear Displacement Adhesion Assay (LiDiAA) platform is the world’s first automated benchtop instrument for high-throughput label-free adhesion measurement of single cells and their collection. LiDiAA simultaneously measures the attachment of thousands of individual cells to a surface within minutes and retrieves post-measurement cells based on their adhesion strength.Human Brain Model of Opioid Addiction and Novel Therapeutics
Current state of the art technologies for CNS disease mechanism studies and drug discovery include rodent models. These models are failing in their predictive capacity in translational medicine applications. Our proprietary human neural organoid models yield clinically corroborated results of opioid use disorders and novel therapeutic drugs identified.Human Brain Disease Models
An avant-garde company making a novel, first in class, Neural Organoid Platform™ that mimics the human central nervous system. To study human brain disease mechanisms To create early diagnostic test To facilitate drug discovery, efficacy and safety testingOpioid Degradation for Treatment of Fentanyl Overdose
NRL researchers have formulated a novel compound that inhibits fentanyl activity by acting as a solution-based neutralization complex to degrade the fentanyl compound before it can bind to the opioid receptor. The drug decreases the bioavailability of fentanyl and results in much less fentanyl efficacy than naloxone used alone.AI-assisted Personal Training Gear to Monitor and Enhance Exercise Performance
The solution consists of a set of tight-fit and sweat-wicking bodywear and a complimentary software. The 16 wearable sensors equipped in bodywear monitors wearer’s movements and muscle activities during exercise. The proprietary AI pose recognition and fatigue prediction algorithms provide users real-time coaching advice to maximize their training performance.AI-based Customized Fabrication Approach for Orthotic Insole Design: 3D Textiles and 3D Printing
An AI-based framework is proposed for prescription of orthotic insoles. Novel 3D spacer fabrics with inlays are incorporated with 3D printing technologies for personalized insole fabrication. It offers good air and moisture permeabilities, and better control of plantar pressures for rehabilitation treatment and accommodate needs of individual patients.Z-pods®
Zylö Therapeutics licensed an innovative topical drug delivery system in 2017. The system, based on silica-derived microparticles called Z-pods®, held the promise of enhancing the bioavailability of many topically applied active ingredients (AIs) for animals, plants, and humans. Zylö has advanced the technology and readied it for commercialization.OpiTracker for Universal Detection of Opioid
OpiTracker is a colorimetric opioid detection technology shown to detect opioid on any surface or in a solution without using a detection device. An eye-readable red to blue color change indicates the presence of opioid. It detects any opioid including fentanyl derivatives that bind to human opioid receptor.