JUNE 13-15, 2022
WASHINGTON, DC
2022 Innovation Showcase Participants
- Showcase Participants with Industry Area: Biotech, Pharma, Health
alfaMAIA
End-to-end diagnostic and informatics platform covering whole chain from sampling to the medical report utilizing two AI systems for rapid prognosis of septic patients.
Movement-Synchronous Electrical Stimulation for Remote Patient Physical Therapy Assistance and Monitoring
Articulate Labs builds wearable medical devices that amplify muscle growth throughout everyday activity to help patients conquer functional limitations and to restore physical capability, starting with the knee.
Chip-scale Magnetocardiography
Today's biomagnetic sensors are large, complex, and require heavy magnetic shielding to mitigate interference from ambient magnetic fields. We have developed a very high resolution magnetic sensor with low size, weight, power, and cost that has enhanced immunity to magnetic interference.
A Fetal Brain Oxygen Monitor
Brimrose Technology together with Johns Hopkins Hospital is developing a sensing system to measure the oxygen levels of the fetus while the mother is in labor. The quick identification of low oxygen levels and rapid correction will dramatically reduce infant mortality and brain disease such as cerebral palsy.
IPASS - non-invasive assessment of intracranial pressure
The IPASS device can assess intracranial pressure (ICP), which is the pressure in the fluid around the brain, without requiring a surgical procedure as in the current gold standard methods. ICP is important int he management of traumatic brain injury (TBI) to prevent secondary brain damage.
Real Time Medical Care Management Artificial Intelligence (Medical AI)
Medical AI predicts disease onset, transition and progression as well as providing the next best action for health care professionals or care navigators to improve health outcomes and decrease costs as much as $100 per member per month our established modules: Renal, Cardiovascular, Diabetes and Behavioral Health (development).
Joint Integrated Lifeline System (JILS)
JILS is a sensor-agnostic software system that integrates disparate data sources from various sensors and allows information display on a user interface to facilitate decision-making. JILS can translate data formats, normalize data, compress data, store data, encrypt the transmissions, and produce actionable output in a variety of network protocols.
Development of the haloanilide, ELP-004 to prevent arthritis-induced bone erosion by inhibiting osteoclast differentiation
ELP-004 is a drug to treat rheumatoid arthritis by directly targeting the cells that cause the bone erosion instead immune components elevated in arthritis. ELP-004 is not immunosuppressive. ELP-004 is a small molecule that is easy and inexpensive to produce and is effective when administered orally.
Novel Hydrogels to Heal Wounds Faster with Less Inflammation
GelSana’s novel hydrogels accelerate wound healing, particularly in inflammatory wounds. Based on their chemistry, the hydrogels provide a moist, protected, anti-inflammatory environment. They are easy to apply and remain stable in the wound. These hydrogels can deliver therapeutics in a sustained manner.
flowDx is a laser-based paper-patterning technology that that radically changes the performance and versatility of current lateral flow tests (LFTs)
Our innovative technology provides a route to delivering a step-change in the performance of LFTs by controlling the fluid-flow within. Laser patterning of the paper materials that build the LFTs allows the ‘clever’ flow-control and helps create next-generation LFTs, which allow for both multiplexing and semi-quantification and have enhanced sensitivity.
Omni-Cool-Breath: A Smart Air-Conditioned Mask
The automatic temperature-controllable mask offers cool air and easy breathing in the mask microclimate for consumers demanding greater comfort and protection under COVID-19 and professionals working in hazardous environments. It reduces temperature by 12°C and humidity by 65% under low voltage via an innovative miniature thermoelectric cooling system.
Antimicrobial thermoplastic polyurethane for medical devices
Inhibit Coatings produce highly effective antimicrobial thermoplastic polyurethanes, which show activity against gram positive, gram negative, antibiotic resistant bacteria, and viruses. The application of our technology into medical devices will reduce incidences of infections caused by these dangerous pathogens, resulting in better patient outcomes.
VestAid: Augmenting Vestibular Rehabilitation Therapy
Successful vestibular rehabilitation (commonly for dizziness) is dependent on patient performance of prescribed at-home gaze stabilization exercises. VestAid is a tablet-based solution that guides patients through these exercises, quantifies performance and compliance, and provides actionable insights to patients and therapists. Through VestAid, we will accelerate the improvement of vestibular patients.
Interstellar Therapeutics
Floral Park, NY
Novel 4D Printing Technique for Treatment of Neurological and Orthopedic Disorders
4D Printing is a step up of 3D printing, allowing transplantation of stem cells in novel biotherapeutics such as Parkinson's Disease, and control over the shape of material even after implantation. We also aim to combat the opioid epidemic with our novel analgesic formulation implant
Prolonged Field Care Realistic Immersive Scenario Engine (PFC RISE)
PFC RISE is a rapidly scalable training and performance analytics ecosystem. Its focus is to help standardize training, provide access to geographically dispersed teams, maximize instructor effectiveness, and assess training performance. Tech Stack includes: Dynamic Scenario Authoring; Scenario Management; Physiology Engine; Human Performance Analytics
Linshom Continuous Predictive Respiratory Sensor & Monitor
Linshom (“to breathe”) is first to deliver continuous predictive respiratory monitoring to the patient bedside and home. We eliminate the morbidity, mortality and cost due to unrecognized respiratory compromise in healthcare with the first PREDICTIVE respiratory device vs. the current RESPONSIVE systems used today.
Probiotic Beer to Enhance Gut Health and Immune System Function
A patent pending process that can guarantee at least one billion live probiotics into every 330 ml of beer. The probiotic strain we have managed to incorporate into the beer can neutralize toxins and viruses in the body, while boosting immunity and improving gut health.
Post-traumatic Stress Disorder Diagnostic and Precision Treatment
Neurovation Labs, Inc. is developing the first-ever objective diagnostic and companion precision medication for Post-traumatic Stress Disorder (PTSD) based on a groundbreaking brain biomarker discovery. PTSD is frequently diagnosed in both military as well as civilians after exposure to trauma. Neurovation Labs is transforming mental healthcare from art to science.
Remote patient monitoring for opioid use disorder treatment
OpiAID provides AI based insights into opioid addiction treatment using biometric data from wearables and behavioral data from EHRs to personalize care.
Tranformational Low Cost/Best Biocomptible/Multifunctional Ultrananocrystallile Diamond (UNCD) Coatings for New Generation Medical Implants
Ultrananocrystalline diamond (UNCDTM) coating (3.5 nm grains) is a new Low-Cost Transformational Material, exhibiting unique properties (hardest coating-same as diamond gem), lowest friction coefficient, totally resistant to chemical corrosion by all fluids, including humans, best biocompatibility (made of Carbon atoms-element of life in human DNA / cells).
MedPad - A Wearable Data Storage device to support transport of computable data as a patient moves
A wearable data storage device that enables computable data, images, audio and video files to move securely and quickly with a wounded warrior/patient ensuring that critical care information is where and when it is needed by care teams as they are moved and transported from austere locations.
Wearable thermoelectrics to heat, cool, and compress for mobile pain relief.
A wearable solution that accelerates return-to-readiness through a combination of heating, cooling, and compression. It provides safe and accurate temperatures (via thermoelectric coolers/Peltier module) and utilizes a novel compression mechanism to deliver safe yet custom treatment based on the needs/pains of the wearer.
A low sample volume and rapid viscosity sensor for early stage injectability/manufacturability detection of biopharmaceuticals
QATCH developed an acoustic microfluidic viscometer that can tell a formulation is injectable/manufacturable at high concentrations using a tiny drop in 5 minutes. Using this tools, biopharma researchers can select molecules that can become injections early in drug development.
Queens College, CUNY
Queens, NY
A quick and safe protocol for virus concentration and nucleic acid extraction
The current innovation uses a simpler and faster method to concentrate viruses from large volumes of fluids such as city wastewater. It allows quick extraction of viral genomic material, which can be further analyzed to detect mutations and thereby identify possible rare variants of concern.
FlowSense™
FlowSense, is a platform wireless, noninvasive wearable skin sensor can detect the presence and magnitude of fluid flow (i.e. blood, lymph and cerebrospinal fluid) in patients with chronic conditions starting with hydrocephalus. Its miniaturized, thin construction is like a bandage which can be used in the hospital and home.
Strathclyde Minor Grove Binders (S-MGBs)
Current and future threats to global biosecurity are predominantly due to infectious pathogens. Our platform technology of molecules bind to DNA at multiple sites to kill pathogens of many different infectious disease types including bacteria, fungi, viruses and parasites, with a unique mechanism of action to delay resistance development.
Automatic Aortic Aneurysm Screening using Deep-Learning Models
A new deep-learning pipeline to evaluate and analyze CT scans of patients to detect and measure aortic aneurysm size.
SimX Virtual Reality Medical Simulation System
The SimX Virtual Reality Medical Simulation System (VRMSS) offers the first fully immersive, multiplayer virtual reality (VR) training where learners can train together in a virtual domain despite being geographically separated at a fraction of the cost of manikin simulation.
Feelix - A Connected Remote Monitoring System
Sonavi Labs is on a mission to improve patient outcomes globally by combining the most advanced acoustic technology available with clinically proven diagnostic AI software. Sonavi Labs created Feelix, a telehealth system that features apps and patented hardware embedded with diagnostic software capable of diagnosing and remotely managing respiratory diseases.
A 3D printed scalable bioreactor for manufacturing of cells and cell derived exosome, proteins, and vaccine
The technology is to develop a new device which can be used in advanced manufacturing of cells and cell-derived products for regenerative and reconstructive therapeutics, injectables and implantable products, cancer and pandemic treatments, and other applications.
Manufacturability of Stretchable Medical Wearable Electronics
High-performance alternatives to rigid electrodes are needed for biomedical use and physiological monitoring. Stretchable electrodes require highly flexible, low-profile, electrically conductive adhesives suited for direct silicon die (unprotected chip) attach. SRS is using its commercially available technology to produce dry electrodes manufacturable in high-volume in the USA.
SurgiField
SurgiField is an ultraportable operating room that fits in a backpack. It offers protection by reducing exposure of surgeons to patient bodily fluids and protecting patients from the surrounding environment. Within hospitals our solution increases operational throughput and decreases cost, and it provides sterility where there is no surgical facility.
SYN-BAC - The first selenium nanoparticle-based antimicrobial dressing for treatment of MRSA infections in skin wounds
Selenium-based nanoparticle (SeNP) treatment for preventive and therapeutic use against bacteria. Our product, SYN-BAC, uses bacteria to produce corresponding therapeutic SeNPs with the aim of using them as antimicrobials towards the same bacteria that produce them. This approach is analogous to a Nanometric Trojan Horse to treating bacterial infections.
Fractionation and Profiling of Heterogeneous Circulating Tumor Cells Using a Hyperuniform-Structured Microchip
The technology is a device used to isolate, identify and categorize in situ the circulating tumor cells (CTCs) that are present in later stages of most forms of cancer utilizing a hyperuniform microchip structure.
Portable In-Vivo Oxidative Stress (IVOS) Biosensor
Oxidative stress occurs when there is imbalance between production and accumulation of toxic free radicals which are normally produced during human metabolism. For the first time, this device enables continuous human metabolism and oxidative stress measurement, which can significantly enhance human performance during CBRN environments and for improved clinical outcomes.
Regulation of assembly status and activity of the proteasome as a non-toxic way to mitigate military relevant muscle atrophy
Loss of skeletal muscle mass and strength is a problem in military-relevant settings including operational stress or post-injury immobilization. In affected muscle cells disassembly of proteins progresses faster than their replenishment. We designed non-toxic small molecules that mitigate the protein loss and restore muscle health in animal model.
Automated Emotional Distress Severity Classification for Children and Adolescents Using Speech Emotion Recognition and AI
The voice-based algorithm TQI is developing will be trained to understand behavioral and emotional tendencies and to anticipate future behaviors to determine if a child’s vocal utterances deviate from age-appropriate linguistic and speech patterns. Improving mental health treatment outcomes requires innovative approaches to measuring the severity of emotional distress.
Broad-Spectrum Antiviral Therapeutics Targeting S1P-Metabolizing Enzymes
Sphingosine-1 Phosphate (S1P) is an enzyme in humans that has been shown to be upregulated by viruses to help them replicate and spread infection. Our work shows that inhibitors of S1P can protect from infection with Influenza A and other clinically relevant viral infections.
University of Notre Dame
South Bend, IN
A Mechanical Device for Breast Cancer Diagnosis
MechDiag device detects breast cancers by analyzing a group of cells from a patient's tissue/blood sample. This is done by the application of stress to determine the cells' resistance (stiffness) to stress. This stiffness property is different in normal cells and can be used to diagnose patients with breast cancer.
Portable platform for mobile ELISA tests
We proposed and prototyped a very accurate, cost effective, small portable ELISA-based system that will be easy to use in every urgent care facility or point-of-care. Previously we demonstrated the first mobile ELISA measuring progesterone level with gold standard accuracy, that was able to support both incubation and plate reading.
NeuroVana - A Non-invasive and Portable Diagnostic-support Device for Brain Injury assessment
It is a non-invasive and portable screening technology to help physicians assess the likelihood of a head injury in minutes and track the recovery. The technology consists of a small and portable ultrasound device that connects with the proprietary software on cloud and gives the results directly on your device.
MIMIX™ Sustained Release Patch
MIMIX Patch stabilizes a wide range of molecules into a thin film strip which can be shipped and stored without refrigeration, eliminating the need for the cold-chain. When applied onto the skin, pharmaceutical-loaded biomaterials dissolve gradually in the body, enabling highly effective medicinal delivery and a more sustained immune response.
A Stimuli Responsive Injectable Hydrogel Platform to Capture and Eradicate Glioblastoma Cells and Glioma Cancer Stem Cells
The technology comprises an injectable hydrogel capable of sustained release of chemokines and sub-lethal electric fields that synergistically direct the selective migration of glioblastoma multiforme and glioma cancer stem cells into the hydrogel through chemotaxis and electrotaxis, respectively. Focused ultrasound can then ablate the entrapped cancer cells.
Personalized Medicine Using Additive Manufacturing
A method for additively manufacturing personalized dosage tablets with different polymer architectures. The method opens the door for achieving 3D printed tablets with improved structural stability and pharmacokinetics for personalized dosage medicine.
Vital Metrix Noninvasive Cardiac Output Measurement
Vital Metrix has developed a non-invasive cardiac output measurement system that is based on analyzing the optical waveform produced by a pulse oximeter. We use model-based data acquisition and AI techniques to correlate the time-varying pleth waveform with pulsatile pressure and blood flow rate.
Compact image-guided system for focal delivery of drugs and electric fields to the brain
System will revolutionize the treatment of neurological and psychiatric disorders by non-invasively delivering and monitoring drugs and therapeutic electric fields using a built-in MRI
Z Field Technologies LLC
Los Angeles, CA
Rapid identification of Coronaviruses including SARS-CoV-2 and detection of its mutations.
Rapid diagnostic assay for the in-field identification of Coronaviruses including SARS-CoV-2 and the detection of mutations in its spike protein from human nasal, buccal or saliva samples. It can be used and easily read by individuals without medical expertise to provide integrated sample-to-answer in less than 30 minutes.
2022 SBIR/STTR AGENCY PARTNERS
